Can leucovorin treat autism? History says, probably not

Parents of autistic children are clamoring for a prescription vitamin promoted by federal health officials. But there's little evidence the drug will help.
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Parents of autistic children are clamoring for a prescription vitamin promoted by federal health officials. But there's little evidence the drug will help.
(Image credit: Inna Kot/iStock)
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The U.S. is giving $1.6 million to researchers to study how the hepatitis B vaccine affects newborns in Guinea-Bissau. Local officials say the trial is suspended. U.S. officials say that's inaccurate.
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Sinners landed a record number of nods, while Avatar: Fire and Ash and Wicked: For Good fell short of their franchise predecessors.
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Opposition parties are slamming the brakes on billions in defense funding as the China escalates military pressure.
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Danielle Brooks and Lewis Pullman presented the nominees for the 98th Academy Awards this morning.
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European leaders hold an emergency summit on a possible U.S.-Greenland deal. And, the Supreme Court weighs whether the president can fire Fed governors.
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NPR's Steve Inskeep speaks with longtime Democrat Rahm Emanuel about politics in the Trump era.
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The president has backed off his threat to take Greenland by force. But his highly inflammatory remarks in Switzerland rattled U.S. allies and threatened to tear down the pillars of the world order.
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A new focus group of Biden-to-Trump voters weighs in on immigration operations and Trump's foreign affairs leadership on Greenland and Venezuela.
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Jack Smith's appearance before the House Judiciary Committee marks the first open testimony about his work after presiding over two federal criminal indictments of President Trump.
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European leaders to meet for emergency summit about the U.S. and Greenland, Trump's statements about Greenland threaten long-standing world order, SCOTUS weighs Trump's power to fire Fed governors.
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The Equal Employment Opportunity Commission voted 2-1 to roll back the agency's 2024 harassment guidance in its entirety. The document gave employers information on what makes up unlawful harassment.
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Some families aren't leaving their homes as aggressive ICE operations continue in Minnesota, leaving their children confined and stressed. Across the Twin Cities, kids are anxious and afraid.
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Israeli forces on Wednesday killed at least 11 Palestinians in Gaza, including two boys, three journalists and a woman, hospitals said, on one of the enclave 's deadliest days since the ceasefire took effect.
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A Cuban migrant held in solitary confinement at an immigration detention facility in Texas died after guards held him down, according to an autopsy report released Wednesday that ruled the death a homicide.
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The National Weather Service issues a litany of notices before and during inclement weather events. They can be important signals on how to respond.
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A large storm system is expected to hit this weekend, with snow and ice from Texas to the Carolinas and up the Eastern seaboard. The winter system could bring more than a foot of snow.
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During a speech in Davos, Switzerland, President Trump ruled out using military force to acquire Greenland. But he left many questions about the U.S. role in the world.
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Republicans on the committee have been seeking to question the Clintons as part of a probe into the government's handling of the Jeffrey Epstein case. The vote sends the matter to the full House.
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The move comes after a federal judge wrote in court document that the "charade of Ms. Halligan masquerading as the United States Attorney … must come to an end."
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Will it be a year of "fractured resilience"? Or "pragmatic empathy"? Will "MOUs" be the next global health strategy? Are we in a new age of "decolonization" — or of "localization"?
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As protestors clash with some 3,000 federal immigration agents in the Twin Cities, we look at the legal issues with law professor Emmanuel Mauleón and Brennan Center for Justice's Elizabeth Goitein.
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The administration wants the authority to fire Lisa Cook, a Fed governor. Experts say that would undermine the independence of the central bank.
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As the festival prepares to move to Colorado, filmmakers and cinephiles gather to celebrate its founder and the future of indie film.
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Far-Flung Postcards is a weekly series in which NPR's international team shares moments from their lives and work around the world.
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President Trump is expected to address affordability at the World Economic Forum today. And, Minnesota officials react after the Justice Department subpoenas them.
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Secretary of State Antony Blinken and his British counterpart, David Lammy, are raising alarms about Iranian ballistic missiles in Russia that threaten Ukraine.
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The state partnered with a nonprofit to wipe out the debts. It also has a plan in place to prevent medical debt for people in specific income brackets.
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In this installment of NPR's "Word of the Week" series we trace the origins of the "cravat" (borrowed from the French "cravate") back to the battlefields of 17th century Europe.
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