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Reblogged by jsonstein@masto.deoan.org ("Jeff Sonstein"):

mpesce@arvr.social ("Mark Pesce") wrote:

Metformin decelerates aging clock in male monkeys

"The results highlighted a significant slowing of aging indicators, notably a roughly 6-year regression in brain aging. Metformin exerts a substantial neuroprotective effect, preserving brain structure and enhancing cognitive ability..."

Very significant finding published in CELL

fwiw i'd be looking closely for any correlation between metformin (which is widely prescribed) and age of onset of dementia

https://www.cell.com/cell/abstract/S0092-8674(24)00914-0